Abstract des Autors

Choline and myo-inositol are dietary supplements ingested under the premise that they facilitate the burning of stored fat. Choline and myo-inositol have been shown to prevent abnormal or excessive liver accumulation of cholesterol and triglycerides in choline and myo-inositol deficient rats. The current study was designed to determine whether the consumption of choline and myo-inositol by non-deficient aerobically trained rats affects the percent liver and carcass fat. Nineteen rats were trained aerobically for ten weeks then randomly assigned to an experimental group fed choline and myo-inositol mixed with their chow, or a control group fed only chow. Rats were sacrificed after 24 more days of aerobic training. Percent carcass and liver fat were determined by a lipid extraction procedure. There was a significant difference in the percent liver fat between groups, with the experimental group having less fat (6.69 +/- 2.23 vs 9.22 +/- 2.91 percent fat; r = 0.05). Percent carcass fat was not significantly different. There was a significant difference in the amount of weight gained during the 24 days of treatment, with the experimental group gaining less weight (5.1 +/- 9.2 vs 11.8 +/- 3.1 g; r < 0.05). The lack of an effect on percent carcass fat indicates that choline plus myo-inositol supplements do not reduce adipose tissue mass but can inhibit weight gain while decreasing liver fat. Verf.-Referat