Altered cellular distribution of hexokinase in skeletal muscle after exercise
Deutscher übersetzter Titel: | Veraenderte zellulaere Verteilung der Hexokinase im Skelettmuskel nach Muskelarbeit |
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Autor: | Van Houten, D.R.; Davis, J.M.; Meyers, D.M.; Durstine, J.L. |
Erschienen in: | International journal of sports medicine |
Veröffentlicht: | 13 (1992), 5, S. 436-438, Lit. |
Format: | Literatur (SPOLIT) |
Publikationstyp: | Zeitschriftenartikel |
Medienart: | Gedruckte Ressource Elektronische Ressource (online) |
Sprache: | Englisch |
ISSN: | 0172-4622, 1439-3964 |
DOI: | 10.1055/s-2007-1021294 |
Schlagworte: | |
Online Zugang: | |
Erfassungsnummer: | PU199211060213 |
Quelle: | BISp |
Abstract
The purpose of this study was to determine the effects of a single period of swim exercise to exhaustion on the cellular distribution of hexokinase in rat skeletal muscle. The gastrocnemius muscle from male rats exercised (n=16) to exhaustion or allowed to remain inactive (n=14) was analyzed for hexokinase activity (HK) in the whole muscle homogenate and the mitochondrial-rich fraction. Although exercise produced a slight, non-significant, increase in HK activity in the whole muscle homogenate (p<0.09), HK activity in the mitochondrial-rich fraction was significantly increased in the exercised muscle (p<0.02). This shift in the cellular distribution of HK is towards the more active mitochondrial bound form and indicates an enhanced regulation of HK activity during physical exercise. Verf.-Referat