Abstract

Three highly trained male sprinters performed sprint training for 14 days at an altitude of 1860 m. Muscle biopsy samples were taken from m. vastus lateralis at sea level, following the training period at altitude and again 2 weeks after returning to sea level. At altitude all 3 subjects showed a decrease in citrate synthase activity (64-77), in hexokinase activity (45-52) and in the activity of lactate dehydrogenase (16-39). Other enzyme activities like 3-OH-acyl-COA dehydrogenase, adenylate kinase and creatine kinase showed variable changes among subjects. The mild to moderate hypoxia and intensive sprint training might have some metabolic effects, which comparatively soon appear as changes in enzyme activity pattern of energy supplying metabolism. Verf.-Referat