Plasma activity of muscle enzymes: quantification of skeletal muscle damage and relationship with metabolic variables

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Deutscher übersetzter Titel:Plasmaaktivitaet der Muskelenzyme: Quantifizierung des Skelettmuskelfaserzerfalls und Beziehung zu Stoffwechselvariablen
Autor:Janssen, G.M.E.; Kuipers, H.; Willems, G.M.; Does, R.J.M.M.; Janssen, M.P.E.; Geurten, P.
Erschienen in:International journal of sports medicine
Veröffentlicht:10 (1989), Suppl. 3, S. 160-168, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource
Sprache:Englisch
ISSN:0172-4622, 1439-3964
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Erfassungsnummer:PU198910040993
Quelle:BISp

Abstract

One hundred fourteen sedentary volunteers (34 +/- 8 years) took part in an endurance training study to be completed after 18-20 months with a marathon. Ultimately, 60 males and 18 females achieved that goal. The training program, carefully supervised, was divided into three periods with a maximum of 45-, 70-, and 110-km week training volume and concluded with a performance race of 15, 25 and 42.2 km, respectively. Three days before and 3 and 5 days after each race, 35 subjects were selected to perform a progressive treadmill test and the remaining subjects participated in field tests of 400 and 1000 m. a significant decrease in half-life time of CK enzyme plasma activity after running long distances in the course of the study from 20 h to 13 h was observed. Based on plasma enzyme activity and supposing that the total enzyme content left the muscle fiber, the estimated amount of muscle demage was found to be small. A gender difference in plasma enzyme activity increase (females demonstrated a lower increase) occurred only after the marathon. Verf.-Referat