Abstract

This study was performed to determine whether an association exists between relative aerobic fitness (fitness index) and lung closing volume (CV). The subject population consisted of 100 healthy nonsmoking adults (50 males and 50 females) divided equally into five age groups; 20-29, 30-39, 40-49, 50-59, and over 60 years. Each subject underwent four to six closing volume and forced vital capacity (FVC) tests followed by a modified Balke maximal oxygen uptake test on a motor-driven treadmill with a constant treadmill speed. Relative VO2 maximum (VO2max, mlO2/kg/min) was used to define subject rank on the fitness index. CV, as a of slow vital capacity (SVC), had a negative linear correlation with the fitness index. Slope of phase III (N2/L) and FEV1/FVC (forced expired volume in 1 s as a of forced vital capacity) also had significant correlation coefficients (r = -0.31, r = 0.24, respectively) with the fitness index. The correlation coefficients, with age partialled from the relationships, between FVC/body weight (kg) and VO2max were r = 0.59 for females and r = 0.43 for males. We hypothesize that the effects of aerobic fitness on lung function may represent a situation where a high level of aerobic fitness affects the aging process of the lung beta-adrenergic nervous system. Verf.-Referat