Skeletal muscle atrophy during immobilization

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Bibliographische Detailangaben
Deutscher übersetzter Titel:Skelettmuskelatrophie bei Immobilisation
Autor:Appell, Hans-Joachim
Erschienen in:International journal of sports medicine
Veröffentlicht:7 (1986), 1, S. 1-5, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource Elektronische Ressource (online)
Sprache:Englisch
ISSN:0172-4622, 1439-3964
DOI:10.1055/s-2008-1025725
Schlagworte:
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Erfassungsnummer:PU198603025656
Quelle:BISp

Abstract

Several apporaches have been made in the past to determine the cellular mechanisms and the biochemical changes during muscle atrophy. Beyond experimental immobilization, muscles were denervated or tenotomy was used to reduce their activity. As Lippmann and Selig pointed out, the results obtained by denervation or tenotomy may not be compared with immobilized muscles since in the first case the afferent impulses are blocked preventing the occurrence of muscular reflexes and in the latter case the muscle is artificially shortened. Therefore, this survey on the effects of disuse of muscles will only focus on immobilization experiments. Verf.-Referat