The effects of exercise on plasma insulin

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Bibliographische Detailangaben
Deutscher übersetzter Titel:Die Wirkung von koerperlicher Belastung auf das Plasmainsulin
Autor:Bjoerntorp, P.
Erschienen in:International journal of sports medicine
Veröffentlicht:2 (1981), 3, S. 125-129, Lit.
Format: Literatur (SPOLIT)
Publikationstyp: Zeitschriftenartikel
Medienart: Gedruckte Ressource Elektronische Ressource (online)
Sprache:Englisch
ISSN:0172-4622, 1439-3964
DOI:10.1055/s-2008-1034597
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Erfassungsnummer:PU198203015958
Quelle:BISp

Abstract

The decrease of plasma insulin levels after physical training is explained mainly by a decreased insulin secretion, but also to a significant degree by an increased peripheral insulin metabolic clearance rate in several peripheraltissues and increased insulin uptake in the liver. The peripheral tissues demonstrate an increased insulin sensitivity, but this seems to be due to factors after the insulin receptor level. An increased turnover of insulin at the receptor level might be postulated. The explanation for the decrease of insulin secretion has been studied extensively. A decreased cortisol secretionmight be a primary factor in physical training, followed by lower insulin levels. Autonomic nervous system adaptations could also be involved in the form of an increased alpha-adrenergic activity. Another alternative is that the effect is mediated via an influence of physical training on a gut incretin factor, facilitating insulin secretion. Finally, it might be con- sidered that the increased insulin sensitivity of muscle following physical training is regulating insulin secretion via feedback mechanisms to the beta cell. Recent demonstrations of inhibited glucose uptake in the liver after exercise facilitates an explanation along these lines. Verf.-Referat