Abstract

The purpose of this study was to investigate whether or not amoxicillin in therapeutic doses could have an influence on maximal aerobic work capacity andsome strength characteristics in trained subjects. Fifteen volunteers were examined once weekly for 4 consecutive weeks, and on these occasions the following variables and parameters were measured: maximum workload attained onthe bicycle ergometer, maximum heart rate, maximum serum lactate concentration, heart rate and serum lactate concentration after 10 min at 80 of the maximum workload attained, maximum isometric extension force of the legs, vertical jump height, and body weight. During the baseline period, the determined variables and parameters did not show any significant difference betweenTest 1 and Test 2 during the 3rd and 4th week of the test period, the subjectsreceived at random either placebo or amoxicillin in therapeutic doses every day for 5 days. The serum amoxicillin levels were determined. After statistical analysis, no influence of amoxicillin or placebo on the parameters and physiologic variables was demonstrable. Verf.-Referat (gekuerzt)